This is a developmental site for SPICE - and the homepage of Andreas Prlic.

The Distributed Annotation System (DAS) is a communication protocol for the exchange of biological annotations. It is motivated by the idea that annotations should not be provided by single centralized databases, but instead be spread over multiple sites. Data distribution, performed by DAS servers, is separated from visualization, which is done by DAS clients. [biodas.org]

SPICE is a browser for the annotations for protein sequences and structures that is based on the DAS protocol. It can be launched from the Ensembl genome browser via the PDB_SPICE - DAS track [demo] or run standalone. It can also be used to visualize multiple structure alignments. [SISYPHUS database][CASP-7] [more info] [publications]

Over the last years DAS has become widely adopted by the community and the DAS registration server now counts more than 250 DAS sources coming from around 40 institutions in 15 countries world wide.

BioJava

I am the developer and maintainer of the protein structure module and some other bits of BioJava. I am also release coordinator for the next release (v1.6). There is also a project to serialize the protein structure modules using Hibernate. To view some stats and the latest nightly BioJava builds please visit the BioJava - CruiseControl page.

Links

Start SPICE using

PDB
UniProt

Javadocs (nightly builds)